Nutrition · Performance · Recovery
TriMagnesium: why the form of magnesium changes everything (and how to choose well)
Magnesium is involved in more than 300 enzymatic reactions. But not all magnesium is created equal: its chemical form determines where it acts, how much is absorbed, and whether the stomach tolerates it. TriMagnesium combines the three most effective forms.
Ask anyone if they take magnesium, and they'll likely say yes, or that they tried and "didn't feel anything." The problem is almost never the magnesium itself: it's the form of magnesium. The difference between magnesium oxide (the most commonly sold in pharmacies) and magnesium bisglycinate is not marketing. It's chemistry and physiology.
At tres60, we formulate TriMagnesium with three different sources of magnesium precisely because no single form covers all the areas where this mineral is needed. This is the logic behind that decision.
The problem with conventional magnesium: bioavailability
When you buy a standard magnesium supplement at a pharmacy, you are almost certainly buying magnesium oxide. It is the cheapest to produce, contains the most elemental magnesium per gram… and is the least absorbed. Its bioavailability is approximately 4%. The remaining 96% reaches the intestine unabsorbed, acts as an osmotic laxative, and is eliminated.
This explains why many people who take magnesium don't notice anything, or only notice altered digestion. It's not that magnesium doesn't work. It's that most of it isn't getting where it needs to go.
The forms of magnesium: not all are equal
| Form | Bioavailability | Digestive Tolerance | Best for |
|---|---|---|---|
| Magnesium Oxide | ~4% | Low (laxative effect) | Occasional constipation. Not for supplementation. |
| Magnesium Citrate | ~16–30% | Medium (can cause diarrhea) | Sporadic use. Not ideal for long-term. |
| Magnesium Chloride | ~20–25% | Medium-low | Topical and sporadic oral use. |
| Magnesium Bisglycinate | High (>80%) | Excellent | Nervous system, sleep, muscle. |
| Magnesium Malate | High | Very good | Cellular energy, fibromyalgia, fatigue. |
| Magnesium Taurate | High | Excellent | Cardiovascular system, nervous system. |
Why TriMagnesium uses three forms and not just one
Magnesium does not act on a single system. It acts on muscles, the nervous system, mitochondria, the heart, and bones. Different forms of magnesium have different affinities for different tissues. Combining the three optimal forms allows us to cover all bases effectively and without digestive side effects.
01 — 788 mg per daily dose
Magnesium Bisglycinate
The form with the highest bioavailability and best digestive tolerance
Bisglycinate is magnesium bound to glycine, an amino acid with its own relaxing properties. This chelation protects magnesium in the digestive tract and facilitates its passage into the blood. It is the most studied form for the central nervous system: it reduces neuronal excitability, modulates stress, and improves sleep quality. At the same time, it relaxes skeletal muscles and reduces the frequency of nocturnal cramps.
Ideal for: sleep, anxiety, cramps, nervous system
02 — 590 mg per daily dose
Magnesium Malate
The most effective form for cellular energy production
Magnesium malate is magnesium bound to malic acid, an intermediate in the Krebs cycle (the process by which cells produce ATP, the body's energy currency). This combination directs magnesium preferentially to the mitochondria, where its effect on energy production is direct. It is the most researched form in the context of chronic fatigue and fibromyalgia, conditions where mitochondrial dysfunction plays a central role.
Ideal for: fatigue, energy, physical performance, fibromyalgia
03 — 250 mg per daily dose
Magnesium Taurate
The form with the highest affinity for the cardiovascular system
Taurate combines magnesium with taurine, an amino acid with cardioprotective properties. This form has a high affinity for heart tissue and the autonomic nervous system: it modulates the electrical excitability of the heart, lowers blood pressure, and supports vascular function. It is the form of choice for individuals with cardiovascular stress, palpitations, or hypertension. Its combination with taurine also enhances magnesium's anxiolytic effect.
Ideal for: cardiovascular health, blood pressure, stress, anxiety
Vitamin B6: the cofactor that completes the formula
TriMagnesium includes 4 mg of vitamin B6 per dose. B6 acts synergistically with magnesium in energy metabolism (ATP synthesis) and in the production of neurotransmitters (serotonin, GABA, dopamine). Without sufficient B6, part of the magnesium cannot perform its neurological function correctly. This combination is documented to improve PMS symptoms, irritability, and mental fatigue.
Signs that you may have a magnesium deficiency
Clinical data
Magnesium deficiency rarely shows up in standard blood tests because only 1% of the body's magnesium is found in plasma. The remaining 99% is inside cells. Serum magnesium can be normal while intracellular magnesium is low. The diagnosis of functional deficiency is based more on clinical signs than laboratory results.
Who is TriMagnesium for?
- People with chronic fatigue or unexplained tiredness.
- Athletes seeking muscle support, fewer cramps, and better recovery.
- People with difficulty sleeping or unrefreshing sleep.
- People with chronic stress or high mental load.
- Women with PMS (magnesium is one of the most documented nutrients for reducing premenstrual symptoms).
- People over 50, whose intestinal absorption of magnesium decreases with age.
- People taking proton pump inhibitors (omeprazole), diuretics, or medications that reduce magnesium absorption.
Synergies with other tres60 products
TriMagnesium + LOGOUT — Deep rest and nervous system support
LOGOUT already includes magnesium bisglycinate in its nocturnal formula. If you add TriMagnesium, you increase the total magnesium intake during the day (especially malate and taurate), reserving the nocturnal effect for LOGOUT. This combination is especially effective for people with high stress loads who need both daytime energy and quality nighttime rest.
TriMagnesium + Vit D3 + K2 — Bones, muscle, and immunity
Magnesium is the enzymatic cofactor that activates vitamin D. Without sufficient magnesium, vitamin D does not convert to its active form even if blood levels rise. This combination ensures that vitamin D works at full capacity for bone, muscle, and immune health.
How and when to take it
2 capsules together at any time of day, preferably with food to improve absorption. If you want to enhance the effect on sleep and recovery, take it with dinner. It does not interfere with daytime sleep: magnesium promotes nervous system relaxation, not direct drowsiness.
TriMagnesium — tres60
Triple source: bisglycinate + malate + taurate. With active vitamin B6. Formulated by doctors. Suitable for vegans and celiacs.
View TriMagnesium →Frequently Asked Questions
Why doesn't TriMagnesium cause diarrhea like other magnesium supplements?
Because it does not contain high doses of magnesium oxide or citrate, which are the forms with the most pronounced intestinal osmotic effect. Bisglycinate, malate, and taurate have a much higher absorption rate, so they reach the bloodstream before the unabsorbed excess has a laxative effect. TriMagnesium's digestive tolerance is excellent even in people with gastrointestinal sensitivity.
Can I take TriMagnesium if I already take LOGOUT?
Yes. LOGOUT includes 100 mg of magnesium bisglycinate in its nocturnal formula. TriMagnesium can be taken during the day (with food) without a problem. The combined intake is within safe ranges and, in fact, this combination is specifically recommended for people with high magnesium demands.
When do the effects of magnesium begin to be noticed?
Effects on sleep and nocturnal cramps are usually perceived within the first 7-14 days. Effects on energy, stress tolerance, and muscle recovery require 4 to 8 weeks of continuous use to be accurately assessed.
Does magnesium interfere with other medications?
Magnesium can reduce the absorption of certain antibiotics (quinolones, tetracyclines) if taken simultaneously. In that case, separate the intake by at least 2 hours. If you take diuretics or cardiovascular medication, consult your doctor about the recommended magnesium intake.
This article is for informational purposes and has been written by the tres60 medical team. It does not replace the advice or diagnosis of a healthcare professional. If you take regular medication, consult your doctor before starting any supplementation.
